
When only one eyelid is drooping, this can occur in two different ways. The tissues above the eyelid—such as the eyebrow, the eyelid’s skin and subcutaneous tissue, fat tissue, or the lacrimal gland—may sag asymmetrically. These cases are usually congenital and considered primarily an aesthetic issue, referred to as pseudo-ptosis. However, sometimes they may indicate an underlying medical condition.
More commonly, unilateral ptosis occurs, where the level of the eyelid margin with the eyelashes is lower. This makes the eye appear smaller or more “narrowed.” The most frequent cause of this condition is the stretching and loosening of the muscles and components that lift the eyelid.
Congenital eyelid drooping occurs when the muscle system responsible for lifting the eyelid fails to develop properly. This condition is rarely bilateral and is not usually inherited genetically. Sometimes, eyelid movements are synchronized with movements of the muscles that control the mouth. This is called Marcus Gunn jaw-winking syndrome.
In adults, unilateral eyelid drooping is most commonly related to age or aging. Frequent eye rubbing, contact lens use, repeated swelling attacks due to allergies or infections, trauma, previous eye or eyelid diseases, and prior eye surgeries can also contribute to unilateral eyelid drooping.
Unilateral eyelid drooping can be quite serious and should always be evaluated by an experienced oculoplastic surgeon. Some underlying orbital or neurological conditions can be very dangerous, potentially leading to blindness or even death.
Orbital tumors can cause unilateral eyelid drooping. During examination, an experienced oculoplastic surgeon can detect this, confirm the diagnosis with appropriate imaging such as CT or MRI, and treat the condition with orbital surgery. If tissue is removed, pathological examination may guide referral to oncology for further treatment.
The most serious neurological causes originate from the brain or spinal cord. Brain tumors, vascular anomalies, nerve palsies, or hemorrhages can cause unilateral eyelid drooping. These can be detected through a comprehensive oculoplastic examination, including eye movements, eyelid function, pupil, and retina assessment.
One important cause of unilateral drooping is Horner’s Syndrome. Its most dangerous causes include a Pancoast tumor of the lung and a silent carotid artery dissection in young patients, which can progress without symptoms and be life-threatening. Diagnosis is made by observing differences in eyelid levels, pupil size, and pupillary light response.
Myasthenia Gravis, a neurological disease usually treated with medication and often not requiring surgery, can also cause unilateral eyelid drooping. Proper oculoplastic or neuro-ophthalmologic evaluation can prevent unnecessary surgery and serious health complications if left undiagnosed.
In unilateral eyelid drooping, one eye appears smaller than the other. This asymmetry is more noticeable in mirrors or photographs due to optical illusion. When drooping is severe, the affected eye may appear even smaller or seem misaligned.
Treatment depends on the underlying cause. If an underlying condition is identified, treating it can also resolve the eyelid drooping. However, in adults, the most common cause is stretching of the eyelid’s muscle system, and surgery is the only effective treatment.
Congenital unilateral eyelid drooping also requires surgery. Different surgical techniques exist; the choice depends on the degree of drooping, function of the eyelid-lifting muscle, response to eye drop testing, and other oculoplastic examinations. Surgery can be performed under local or general anesthesia, depending on the situation.
Given the potential underlying conditions, eyelid drooping should always be evaluated by an experienced oculoplastic surgeon. A surgeon skilled in eyelid surgical techniques will provide significant benefits both during the surgery and in postoperative care, ensuring the long-term health of your eyes.